Research Associate/Senior Research Associate, Discovery Biology

San Diego, CA

  • We are seeking a creative, highly motivated, responsible and dynamic Research Associate/Senior Research Associate to join our R&D division to contribute to high-impact and fast-paced research and drug discovery.
  • This position is a full-time position in the company’s San Diego headquarters.

Specific Responsibilities

  • Perform tissue culture work including mammalian cell lines and primary cells.
  • Develop appropriate in vitro biochemical, molecular and cell-based assays including cytotoxicity, cell proliferation, high-content imaging, and luminescence-based assays to screen and develop small-molecule therapeutics.
  • Design and execute in vitro cell and molecular biology assays including, but not limited to, RNA extraction, qRT-PCR, FACS, SDS-PAGE, Western Blotting, ELISA, immunohistochemistry, immunofluorescence as necessary to support target discovery, validation, mechanism of action, drug development and biomarker selection.
  • Plan and execute scientific experiments to detect and characterize mRNA splicing, as required.
  • Analyze and document experimental data in electronic notebooks in a timely and accurate manner in accordance with the company rules.
  • Present scientific data to colleagues and assist in the preparation of internal and external presentations (presentations, posters, publications).
  • Perform additional general duties to support the safe and efficient operation of the laboratory as required.
  • Efficiently managing scheduling of studies, and managing own time to complete assigned work by due date.

Requirements

  • B.S. or M.S. in Biological Sciences or related field with 2+ years of laboratory experience. Prior industry experience is a plus.
  • Broad knowledge of Cellular Biology, Molecular Biology, Biochemistry, Histology Imaging and in vitro assay development.
  • Strong expertise in mammalian cell culture (adherent & suspension cultures) and cell-based assays (e.g. proliferation, viability, luminescence assays).
  • Proficiency with molecular biology techniques, such as qRT-PCR, RNA-seq, Western blotting, ELISA, HTRF.
  • Broad knowledge and experience with alternative splicing a plus.
  • Proven ability to collaborate in a team environment and work independently.
  • Excellent oral and written communication skills.
  • Must have strong work ethic, able to multi-task, detail-oriented and enthusiastic for laboratory work.
  • Must be a team-player, punctual and reliable, dependable and flexible in adapting to change in a multi-disciplinary, fast-paced work environment
  • Level will be commensurate with experience

Please submit your resume or additional inquiries to apply@samumed.com. Please include the complete title of the position for which you are applying in the subject line of your email. Emails that do not include this information will be disregarded. NO PHONE CALLS PLEASE.