Scientist / Senior Scientist, Musculoskeletal Biology

San Diego, CA

  • We are seeking a responsible, dynamic, creative and highly motivated Scientist / Senior Scientist to join our R&D division to contribute to preclinical research and discovery.  
  • This position is a full-time position in the company’s San Diego headquarters.

Specific Responsibilities

  • Independently leading the identification and characterization of novel targets and mechanisms of tissue degeneration and disease, especially in the context of the musculoskeletal system (e.g., bone, muscle, cartilage, tendon, ligaments)
  • Managing multiple drug development programs for musculoskeletal diseases
  • Managing pre-clinical and non-clinical development for multiple candidate molecules towards IND filing.
  • Developing appropriate in vitro biochemical, molecular and cell-based assays to screen and develop small-molecule therapeutics
  • Designing and executing studies with appropriate animal models (mouse/rat) to test candidate compounds
  • Interacting routinely with Samumed’s Bioinformatics team to integrate knowledge and develop an understanding of complex biological systems
  • Assisting team members in integrative experiments that measure the biological response of in vitro and in vivo systems to pharmacological modulation
  • Engaging in data analysis, presenting results, and working collaboratively with others to achieve objectives and timelines
  • Managing 2+ Research Associates as required
  • Analyzing and documenting experimental data in electronic notebooks in a timely and accurate manner in accordance with the company rules
  • Presenting scientific data to colleagues and assisting in the preparation of internal and external presentations (oral, posters, and publications)

Requirements

  • Ph.D. in Biological Sciences or related field
  • PhD with at least 4+ years of pharmaceutical/ biotechnology industry experience.
  • Deep knowledge and experience in the biology of the Musculoskeletal System.
  • Previous drug development expertise is necessary.
  • Broad knowledge of Cellular Biology, Molecular Biology, Biochemistry, Histology Imaging and in vitro assay development
  • Proficiency in mammalian cell culture, cellular, molecular assays and associated techniques
  • Experience with musculoskeletal and/or degenerative disease animal models, dosing (IP, IV, PO, SC), behavioral measurements and tissue harvesting required
  • Publication record is desirable
  • Previous managerial experience preferred. Proven ability to collaborate in a team environment and work independently
  • Excellent oral and written communication skills
  • Outstanding organizational and critical thinking skills
  • Must have strong work ethic, able to multi-task, detail-oriented and enthusiastic for laboratory work
  • Must be a team-player, punctual and reliable, dependable and flexible in adapting to change in a multi-disciplinary, fast-paced work environment
  • Level and compensation will be commensurate with experience

Please submit your resume or additional inquiries to apply@samumed.com. Please include the complete title of the position for which you are applying in the subject line of your email. Emails that do not include this information will be disregarded. NO PHONE CALLS PLEASE.