Scientist / Senior Scientist, Musculoskeletal Biology

San Diego, CA

  • We are seeking a responsible, dynamic, creative and highly motivated Scientist / Senior Scientist to join our R&D division to contribute to preclinical research and discovery.  
  • This position is a full-time position in the company’s San Diego headquarters.

Specific Responsibilities

  • Independently leading the identification and characterization of novel targets and mechanisms of tissue degeneration and disease, especially in the context of the musculoskeletal system (e.g., bone, muscle, cartilage, tendon, ligaments)
  • Managing multiple drug development programs for musculoskeletal diseases
  • Managing pre-clinical and non-clinical development for multiple candidate molecules towards IND filing.
  • Developing appropriate in vitro biochemical, molecular and cell-based assays to screen and develop small-molecule therapeutics
  • Designing and executing studies with appropriate animal models (mouse/rat) to test candidate compounds
  • Interacting routinely with Samumed’s Bioinformatics team to integrate knowledge and develop an understanding of complex biological systems
  • Assisting team members in integrative experiments that measure the biological response of in vitro and in vivo systems to pharmacological modulation
  • Engaging in data analysis, presenting results, and working collaboratively with others to achieve objectives and timelines
  • Managing 2+ Research Associates as required
  • Analyzing and documenting experimental data in electronic notebooks in a timely and accurate manner in accordance with the company rules
  • Presenting scientific data to colleagues and assisting in the preparation of internal and external presentations (oral, posters, and publications)

Requirements

  • Ph.D. in Biological Sciences or related field
  • PhD with at least 4+ years of pharmaceutical/ biotechnology industry experience.
  • Deep knowledge and experience in the biology of the Musculoskeletal System.
  • Previous drug development expertise is necessary.
  • Broad knowledge of Cellular Biology, Molecular Biology, Biochemistry, Histology Imaging and in vitro assay development
  • Proficiency in mammalian cell culture, cellular, molecular assays and associated techniques
  • Experience with musculoskeletal and/or degenerative disease animal models, dosing (IP, IV, PO, SC), behavioral measurements and tissue harvesting required
  • Publication record is desirable
  • Previous managerial experience preferred. Proven ability to collaborate in a team environment and work independently
  • Excellent oral and written communication skills
  • Outstanding organizational and critical thinking skills
  • Must have strong work ethic, able to multi-task, detail-oriented and enthusiastic for laboratory work
  • Must be a team-player, punctual and reliable, dependable and flexible in adapting to change in a multi-disciplinary, fast-paced work environment
  • Level and compensation will be commensurate with experience

Please submit your resume or additional inquiries to apply@samumed.com. Please include the complete title of the position for which you are applying in the subject line of your email. Emails that do not include this information will be disregarded.