Scientist I, Oncology (#2)

San Diego, CA

  • We are seeking a responsible, dynamic, creative and highly motivated Scientist to join our oncology team in the R&D division to contribute to preclinical research programs aimed at the development of treatments for cancer.  
  • This position is a full-time position in the company’s San Diego headquarters.

Specific Responsibilities

  • Driving projects to rationally combine targeted therapies in in vitro and in vivo models of a variety of tumor types
  • Developing functional immune cell-based assays including T cell activation and proliferation assays, tumor cell cytotoxicity assays and co-cultures with multiple cell types
  • Designing and executing supporting assays (immunophenotyping, cytokine profiling, qPCR, ELISA and/or western-blot analysis) to assess target modulation levels and downstream effects
  • Analyzing and documenting experimental data in electronic notebooks in a timely and accurate manner in accordance with the company rules
  • Presenting scientific data in team meetings and assisting in the preparation of internal and external presentations (oral, posters, and publications).

Requirements

  • Ph.D. in Immunology, cancer biology or related field
  • 2+ years post-graduate experience in immunology, tumor immunology or closely related field in industry. 
  • Expertise in in vivo tumor models (i.e., xenograft, PDX) in both immunocompetent and immunocompromised mice
  • Proficiency in functional immune cell-based assays (e.g., T cell activation and MLR assays)
  • Expertise in multi-color flow cytometry, gene expression (qRT-PCR), western-blot
  • Proficiency in isolation of PBMCs and tumor-infiltrating lymphocyte profiling in mouse syngeneic cancer models is highly desirable
  • Proven ability to collaborate in a team environment and work independently
  • Ability to design, plan, execute, interpret and troubleshoot experiments with minimal supervision
  • Excellent oral and written communication skills
  • Must have strong work ethic, able to multi-task, detail-oriented and enthusiastic for laboratory work
  • Must be a team-player, punctual and reliable, dependable and flexible in adapting to change in a multi-disciplinary, fast-paced work environment
  • Level will be commensurate with experience

Please submit your resume or additional inquiries to apply@samumed.com. Please include the complete title of the position for which you are applying in the subject line of your email. Emails that do not include this information will be disregarded. NO PHONE CALLS PLEASE.