Scientist I, Oncology (#2)

San Diego, CA

  • We are seeking a responsible, dynamic, creative and highly motivated Scientist to join our oncology team in the R&D division to contribute to preclinical research programs aimed at the development of treatments for cancer.  
  • This position is a full-time position in the company’s San Diego headquarters.

Specific Responsibilities

  • Driving projects to rationally combine targeted therapies in in vitro and in vivo models of a variety of tumor types
  • Developing functional immune cell-based assays including T cell activation and proliferation assays, tumor cell cytotoxicity assays and co-cultures with multiple cell types
  • Designing and executing supporting assays (immunophenotyping, cytokine profiling, qPCR, ELISA and/or western-blot analysis) to assess target modulation levels and downstream effects
  • Analyzing and documenting experimental data in electronic notebooks in a timely and accurate manner in accordance with the company rules
  • Presenting scientific data in team meetings and assisting in the preparation of internal and external presentations (oral, posters, and publications).

Requirements

  • Ph.D. in Immunology, cancer biology or related field
  • 2+ years post-graduate experience in immunology, tumor immunology or closely related field in industry. 
  • Expertise in in vivo tumor models (i.e., xenograft, PDX) in both immunocompetent and immunocompromised mice
  • Proficiency in functional immune cell-based assays (e.g., T cell activation and MLR assays)
  • Expertise in multi-color flow cytometry, gene expression (qRT-PCR), western-blot
  • Proficiency in isolation of PBMCs and tumor-infiltrating lymphocyte profiling in mouse syngeneic cancer models is highly desirable
  • Proven ability to collaborate in a team environment and work independently
  • Ability to design, plan, execute, interpret and troubleshoot experiments with minimal supervision
  • Excellent oral and written communication skills
  • Must have strong work ethic, able to multi-task, detail-oriented and enthusiastic for laboratory work
  • Must be a team-player, punctual and reliable, dependable and flexible in adapting to change in a multi-disciplinary, fast-paced work environment
  • Level will be commensurate with experience

Please submit your resume or additional inquiries to apply@samumed.com. Please include the complete title of the position for which you are applying in the subject line of your email. Emails that do not include this information will be disregarded.